Ectopic pregnancy is a high risk condition that occurs in 19 percent of reported pregnancies the condition is the leading cause of pregnancy related death in the first trimester if a woman of . The diagnosis of ectopic pregnancy can be difficult and protracted a diagnosis of pregnancy of unknown location should trigger further diagnostic pathways and follow up until the final outcome of the pregnancy is known medical management with methotrexate is successful for small stable ectopic pregnancies. The diagnosis and management of pregnancy of unknown location will not be covered unfortunately women still die from ectopic pregnancy with six maternal deaths reported between 2006 and 2008 however the case fatality rate has decreased over recent years suggesting that earlier diagnosis and treatment may have made an impact. Though the cases of ectopic pregnancy are on rise the incidence of rupture of ectopic pregnancy and maternal deaths has declined because of early diagnosis and management ectopic pregnancy still accounts for 4 to 10 of pregnancy related deaths and leads to a high incidence of ectopic site gestations in subsequent pregnancies. Diagnosis and management of ectopic pregnancy green top guideline no 21 rcog aepu joint guideline november 2016 please cite this paper as elson cj salim r potdar n chetty m ross ja kirk ej on behalf of the royal college of
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