Therefore the quinolones cover the modern era of antibiotic drug discovery not only have the quinolones been used widely but they have also been intensively studied and as such have probably added more to our knowledge of antimicrobial science than any other class of antibiotic or antimicrobial chemotherapeutic agent. Quinolones for the treatment of skin soft tissue bone andprosthetic joint infections the role of fluoroquinolones in the therapy and prophylaxisof neutropenic patients with cancer less usual indications mycobacterial brucella yersiniafrancisella and other infections the quinolones future prospects series title milestones in drug . Since the introduction of ciprofloxacin in 1987 fluoroquinolones have expanded far beyond their early role in the treatment of urinary tract infections clinical applications beyond genitourinary tract infections include upper and lower respiratory infections gastrointestinal infections gynecologic infec tions sexually transmitted diseases and some skin and soft tissue infections. Quinolones are a type of antibiotic antibiotics kill or inhibit the growth of bacteria there are five different quinolone classes in addition another class of antibiotic called fluoroquinolones were derived from quinolones by modifying their structure with fluorine. Milestones in drug therapy mdt series editors prof dr michael j parnham pliva research institute prilaz baruna filipovica 25 10000 zagreb croatia prof dr j bruinve1s infarm sweelincklaan 75 nl 3723 jc bilthoven the netherlands fluoroquinolone antibiotics edited by ar ronald and de low springer basel ag editors alian r ronald
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